About Us
History of Innovation

Combination vaccines, those that protect against multiple diseases, are one of the strengths of Sanofi Pasteur's product range. They offer the advantage of simplifying vaccination schedules, decreasing the number of injections and the health-related costs.

Since the beginning of the 20th century, many innovative discoveries have been made in vaccines.

 
1907
Sera production1
 
1922
First tetanus vaccine2
 
1939
New application of the percutaneous reaction
 
1939
First use of the Mérieux tuberculin
 
1946
Anti-pertussis serum
 
1953
Yellow fever vaccine
 
1955
First Salk (inactivated) polio vaccine (injectable)3
 
1960
Lépine (inactivated) polio vaccine (injectable)
 
1962
First Sabin (attenuated) polio vaccine (oral)
 
1963
Tuberculin multipuncture ring
 
1968
Measles vaccine
 
1968
Influenza vaccine
 
1970
Rubella vaccine (human diploid origin)
 
1974
First group A Meningococcal vaccine
 
1975
First groups A+C Meningococcal vaccine
 
1975
Vaccine against diphtheria, tetanus, pertussis and polio (injectable)
 
1977
First rabies vaccine (human diploid origin)
 
1981
First plasmatic hepatitis B vaccine
 
1982
First injectable Salk polio vaccine (on Vero cells)
 
1985
First rabies vaccine (on Vero cells)4
 
1986
MMR (Measles-Mumps-Rubella) vaccine
 
1987
Hepatitis B vaccine (based on genetic engineering)
 
1987
First Haemophilus influenzae type b conjugate vaccine
 
1988
First oral Sabin polio vaccine (Vero cells)
 
1988
First typhoid vaccine (polysaccharides)
 
1992
DT acellular pertussis vaccine for adults5
 
1993
Vaccine against diphtheria, tetanus, pertussis (whole cell) and Haemophilus influenzae type b
 
1993
First pentavalent diphtheria, tetanus, pertussis (whole cell), poliomyelitis and Haemophilus influenzae type b vaccine (awarded the Galien Prize in 1994)
 
1996
Hepatitis A vaccine6
 
1997
First pentavalent vaccine with acellular pertussis
 
1998
Diphtheria, tetanus, pertussis (acellular) and poliomyelitis vaccine
 
1999
Adult booster against tetanus, diphtheria, and polio
 
1907
First quadrivalent conjugate vaccine against meningococcal disease7
 
2005
Conjugate vaccine against meningococcal meningitis (A+C+W+Y)
Monovalent oral polio vaccine (type 1)
 
2007
H5N1 pandemic influenza vaccine (to anticipate a potential pandemic)
 
2008
Smallpox vaccine (to anticipate a potential bioterrorism attack)
First micro-needle vaccine against influenza
 
2009
A(H1N1) monovalent influenza vaccine
 
2010
First high-dose influenza vaccine, designed specifically for people 65 years of age and older8
 
2013
First hexavalent diphtheria, tetanus, pertussis (acellular), poliomyelitis, Haemophilus influenzae type b and Hepatitis B vaccine9
 
2015
First dengue vaccine
 
2016
First recombinant protein-based influenza vaccine10



References:
  1. Institut Biologique Mérieux
  2. Institut Mérieux
  3. By Connaught Laboratories, bought by Institut Mérieux in 1989
  4. Merger of Institut Mérieux & Institut Pasteur Production created in 1973. Pasteur Vaccins is founded
  5. By Pasteur Mérieux Sérums & Vaccins, created in 1990.
  6. Pasteur Mérieux Connaught.
  7. By Aventis Pasteur, new name of Pasteur Mérieux Connaught after the merger of Rhône-Poulenc and Hoechst Life Sciences activities in 1999, to form a single company, Aventis.
  8. Fluzone HD Fact Sheet (Download)
  9. Sanofi Pasteur. Data on File.
  10. Sanofi completes acquisition of Protein Sciences Press Release (Find out more)